In Japan, non-surgical regenerative medical treatments involving stem cells fall into three categories: 1. Stem Cell Supernatant Treatment 2. Stem Cell Secretome Treatment 3. Stem Cell Treatment
Secretome Explained
When stem cells are cultured, they release various beneficial substances into the culture medium, collectively called secretome. The secretome includes exosomes, cytokines (growth factors and neurotrophic factors), micro-vesicles, proteins, hormone-like substances, and immunomodulatory substances. Current studies and clinical trials suggest thatthe effectiveness of stem cell treatments comes from these substances, not fromthe stem cells themselves.
*Image of Stem Cells releasing effective substances in the culture medium solution
*Image of Stem Cell Secretome solution with secretomes as they are (no actual stem cells are contained in the solution)
*Image of Stem Cell Supernatant solution which is the concentrate of Stem Cell Secretomes
Stem Cell Supernatant Treatment
Stem Cell Supernatant Treatment uses a concentrated solution of secretomes created through advanced technologies such as secretome centrifugation, etc. This treatment is particularly recommended for visitors to Tokyo due to its safety, effectiveness, and short treatment time with no downtime.
Key Points:
Components: Higher concentration of exosomes, growth factors, and other active substances.
Procedure: Injects or applies the supernatant solution deep into the skin.
Sources: Derived from umbilical cord or adipose tissue of healthy female donors in Japan.
Safety: Thorough sanitization and screening processes ensure safety.
Availability: Offered only at accredited clinics in Japan.
Stem Cell Secretome Treatment
Stem Cell Secretome Treatment utilizes the culture medium solution containing secretomes without the actual stem cells. This treatment injects or applies the secretome solution deep into the skin.
Mechanism: Infuses secretome into the patient’s body.
Components: Exosomes, growth factors, and cytokines.
Application: Approved for cosmetic use in Japan, often used in "Stem Cell Facial Treatment" at medical spas in Tokyo.
Stem Cell Treatment
Stem Cell Treatment involves injecting actual stem cells into the patient’s body. This process can be autologous or allogeneic.
Autologous Stem Cell Treatment:
Procedure:
Tissue extraction from the patient's body.
Stem cell culturing in the lab.
Injection of cultured stem cells back into the patient via IV drip or local injection.
Duration: Approximately 6 weeks with a few days of downtime after tissue extraction.
Recommendation: Not ideal for short-term visitors but available for those with sufficient time.
Allogeneic Stem Cell Treatment:
Procedure: Uses donor stem cells cultured in the lab and injected into the patient.
Risks: Higher risk due to potential immune response and complications from foreign cells.
Practice: No longer practiced in Japan to avoid accidents and complications.
Summary
Stem Cell Supernatant Treatment: Recommended for its high efficacy and safety.
Stem Cell Secretome Treatment: Uses secretome-rich culture medium without actual stem cells.
Stem Cell Treatment: Direct use of stem cells, mainly for longer-term, autologous treatments.
Our website connects visitors with top clinics in Tokyo that offer these advanced treatments using stem cell supernatant solutions. For more detailed information or to book a treatment, please contact us.
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